http://www.medicalnewstoday.com/releases/278565.php
http://www.sciencedaily.com/releases/2014/06/140624093320.htm
Ketamine and Depression: "Special K", or Ketamine, has shown important benefits when used to treat patients with severe depression who have not responded to traditional anti-depressants. Professor Colleen Loo at the University of New South Wales reports that sub-cutaneous (under the skin) placement of Ketamine provides instant improvement in patients with atypical depression. Ketamine has been traditionally used as an animal anesthetic and became more widely known by the general public as it became associated with date rape. These researchers point out the necessity of further study needed to develop dose, schedule and duration of effectiveness.
http://www.medicalnewstoday.com/articles/278070.php